2024 Larran

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Jul 20, 2019 · Sorry for the print in video, I received uncut rubys, worth about 54k. 8699. Larran is a non-player character found north-east of the Chaos Temple by his small chest . If players speak to him while wearing a ghostspeak amulet, they will learn that he was once a wealthy merchant who stored his possessions in a small and big chest in the Wilderness, where he believed few would attempt to open them. Larran, Inc in Fenton, MO received a Paycheck Protection Loan of $137,615 through Midwest BankCentre, which was approved in April, 2020. This loan's status is reported by the SBA as "Paid in Full", which includes both loans repaid and those fully forgiven from repayment under PPP guidelines. The loan's status was last updated by the SBA in ... Larran's Chest Needs to be More Rewarding. When you put it in context, the Larran's Keys are supposed to be part of a Wilderness Rejuvenation effort that's goal is make/update content that will entice more players to use the Wilderness. It sounds great; tons of potential to creatively reward players willing to train in the wildy, as well as re ...The big larran's key chest is basically a safezone LOL! : r/2007scape. Good job jagex. The big larran's key chest is basically a safezone LOL! You just go 2 steps north of the chest up to the ladder and you end up in a 1x1 spot where a pker can not even attack you at. High risk high reward hu?? This isnt new..Larran's key is a key obtained from killing monsters while on a Slayer task given by Krystilia. It is used to open Larran's small and big chests. The exact odds of receiving a key scales with the monster's Combat level. For levels 1-80, the probability follows a curve between 1/1972 at level 1 to 1/100 at level 80. Unlock, Check. Examine. A secure chest. Map. Advanced data. Object ID. 34829. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player.The crystal key is created by combining a tooth half of key with a loop half of key, displaying the message, "You join the two halves of the key together." Key halves can be obtained as rewards from Barrows, the Gnome Restaurant minigame, Managing Miscellania, Treasure Trails, looting magpie implings, random events, the rare drop table, spoils of war, etc. Larran is a high school graduate. 45 Highlands Forest La, Oxford, GA 30054-3046 is the last known address for Larran. Seven persons linked to this address. Their names are Courtney Jones, Joshua Jones, and five others. Larran uses the landline number (770) 787-7980 (Bellsouth Telecommunications, LLC).What Is a 'larrans key'. Larran's key is a key that is obtained whilst being on a wilderness slayer task obtained from Krystilia. The rate of receiving a key is varied by the task you have, the higher the combat level the more common of a chance you have of receiving a key.The crystal key is created by combining a tooth half of key with a loop half of key, displaying the message, "You join the two halves of the key together." Key halves can be obtained as rewards from Barrows, the Gnome Restaurant minigame, Managing Miscellania, Treasure Trails, looting magpie implings, random events, the rare drop table, spoils of war, etc.Tiziano Barbui # 1 , Valerio De Stefano # 2 , Alessandra Carobbio 3 , Alessandra Iurlo 4 , Alberto Alvarez-Larran 5 , Beatriz Cuevas 6 , Francisca Ferrer Marín 7 , Alessandro M Vannucchi 8 , Francesca Palandri 9 , Claire Harrison 10 , Hassan Sibai 11 , Martin Griesshammer 12 , Massimiliano Bonifacio 13 , Elena M Elli 14 , Chiara Trotti 15 ...Graveyard of Shadows. A second place you can find green dragons in Old School RuneScape is just north of the Graveyard of Shadows, which itself is just north of the Ferox Enclave. There are five dragons in this location. This is a nice location due to its proximity to the Ferox Enclave, which is a safe settlement within the Wilderness.Manuel Larrán-Jorge [email protected] Español. Doctor en Ciencias Económicas y Empresariales por la Universidad de Cádiz, España. Catedrático universitario, Departamento de Economía Financiera y Contabilidad. Decano de la Facultad de Ciencias Económicas y Empresariales de la Universidad de Cádiz.Juan-Carlos Hernández-Boluda 1 , Arturo Pereira 2 , Alberto Alvarez-Larran 3 , Ana-Africa Martín 4 , Ana Benzaquen 5 , Lourdes Aguirre 6 , Elvira Mora 7 , Pedro González 8 , Jorge Mora 9 , Nieves Dorado 10 , Antonia Sampol 11 , Valentín García-Gutiérrez 12 , Oriana López-Godino 13 , María-Laura Fox 14 , Juan Luis Reguera 15 , Manuel ... 24291. The Dagon'hai robe top is a piece of magic armour obtained as a rare loot from Larran's big chest. It is part of the Dagon'hai robes set, and requires level 70 Magic and 40 Defence to wear. It can be stored in a magic wardrobe in a player owned house. Attack bonuses. Silvina Larran Passion fruit (Passiflora edulis Sims.) is a subtropical fruit recently cultivated in Misiones Province, Argentina. In spring 1997, a severe epidemic of anthracnose was observed.Pablo Larraín was born in Santiago, Chile. He is a director, writer and producer, known for Spencer (2021), Jackie (2016), El Club (2015), NO (2012), among others. Together with his brother Juan de Dios Larraín, they founded Fabula in 2004, one of the most prolific production companies in Latin America. More at IMDbPro. Contact info. Agent info. Current Guide Price 134.3k. Today's Change - 2,154 - 1%. 1 Month Change - 34.4k - 20%. 3 Month Change 48.8k + 57%.The optimal duration of treatment with vitamin K antagonists (VKA) after venous thromboembolism (VTE) in patients with Philadelphia-negative myeloproliferative neoplasms (MPNs) is uncertain. To tackle this issue, we retrospectively studied 206 patients with MPN-related VTE (deep venous thrombosis of …Currently working as a postdoc researcher at the Center for Research in Agricultural Genomics (CRAG) in Spain. My research line is focused on the mechanisms controlling epigenetic silencing in plants. The lesser demon is the sixth strongest monster in free-to-play, only beaten by the ankous in the Stronghold of Security, the level 85 skeletons, greater demons in the Wilderness, and the bosses Obor and Bryophyta . Safespot location for lesser demons in Chasm of Fire. The Chasm of Fire is one of the best locations for slaying lesser demons.Manuel Larrán-Jorge [email protected] Español. Doctor en Ciencias Económicas y Empresariales por la Universidad de Cádiz, España. Catedrático universitario, Departamento de Economía Financiera y Contabilidad. Decano de la Facultad de Ciencias Económicas y Empresariales de la Universidad de Cádiz. 17/1. 78/20. Source: CricketArchive, 24 December 2022. Lauren Winfield-Hill ( née Winfield; born 16 August 1990) is an English cricketer who currently plays for Yorkshire, Northern Diamonds, Oval Invincibles, Melbourne Stars and England. She plays as a right-handed batter and occasional wicket-keeper. The lesser demon is the sixth strongest monster in free-to-play, only beaten by the ankous in the Stronghold of Security, the level 85 skeletons, greater demons in the Wilderness, and the bosses Obor and Bryophyta . Safespot location for lesser demons in Chasm of Fire. The Chasm of Fire is one of the best locations for slaying lesser demons.Thinking of names? Complete 2021 information on the meaning of Larran, its origin, history, pronunciation, popularity, variants and more as a baby boy name.The clinical significance of resistance/intolerance to hydroxycarbamide (HC) was assessed in a series of 890 patients with polycythaemia vera (PV). Resistance/intolerance to HC was recorded in 137 patients (15·4%), consisting of: need for phlebotomies (3·3%), uncontrolled myeloproliferation (1·6%), … 97K views 3 years ago. Hey guys, today I am going to be testing out wilderness slayer after the new update. Yesterdays update released the new Larran's chest, as well as the new wines of zamorak ...Jan 18, 2023 · Hindrigo "Kiko" Lorran was the chef on Below Deck Mediterranean season 5 and continues to live out his dream as a professional chef to this day. During his time on the show, Kiko was able to develop close relationships with his crew members, especially Chief Steward Hannah Ferrier. Kiko may have been friendly with the crew, but his cooking did ... Sep 17, 2019 · Larran's Key Buffs: Bolts/ Arrows- I'm completely fine with this +1; Cerberus Boots- Maybe just dragon boots (or) or something not Cerberus boots -1; Dominion Tower gloves- Again this isn't necessary -1; Remove Godswords- I kind of like the variety and ease of getting the lesser used Godswords and each of them have a place in terms of ... 8699. Larran is a non-player character found north-east of the Chaos Temple by his small chest . If players speak to him while wearing a ghostspeak amulet, they will learn that he was once a wealthy merchant who stored his possessions in a small and big chest in the Wilderness, where he believed few would attempt to open them. Hindrigo "Kiko" Lorran was the chef on Below Deck Mediterranean season 5 and continues to live out his dream as a professional chef to this day. During his time on the show, Kiko was able to develop close relationships with his crew members, especially Chief Steward Hannah Ferrier. Kiko may have been friendly with the crew, but his cooking did ...The crystal key is created by combining a tooth half of key with a loop half of key, displaying the message, "You join the two halves of the key together." Key halves can be obtained as rewards from Barrows, the Gnome Restaurant minigame, Managing Miscellania, Treasure Trails, looting magpie implings, random events, the rare drop table, spoils of war, etc.A secure chest. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player. Though sharing the same loot compared to Larran's small chest, the quantities obtained from the big chest are much ...What Is a 'larrans key'. Larran's key is a key that is obtained whilst being on a wilderness slayer task obtained from Krystilia. The rate of receiving a key is varied by the task you have, the higher the combat level the more common of a chance you have of receiving a key.Clinical characteristics, prognosis and treatment of myelofibrosis patients with severe thrombocytopenia Recombinant human erythropoietin (rHuEPO) is an effective treatment for the anaemia that occurs secondary to various conditions, but its role in myelofibrosis with myeloid metaplasia (MMM) is not well established. rHuEPO, at an initial dose of 10 000 U thrice a week, was given to 20 patients with MM … just checked, the minimum for each key is 400k but the highest i see is 450k. 4. Spixican • 1 yr. ago. Wow that is a pricey key. I wouldn't had guessed that much. I have a newfound appreciation to Larran keys. I already loved them but now even more! 4. Past-Boat-755 • 1 yr. ago.Larran was born in August 20, 1960 Larran has 6 phone numbers Larran has 1 relative Larran has 5 past addresses Larran has 3 emails Larran has 3 associates by phone number Larran has 71 associates by address Larran is married Larran’s home type is Multiple Family Dwelling Unit Larran has resided at the current address since 2022 The value of the property where Larran lives is 157 200 USD ...Patients with essential thrombocythemia (ET) have an increased frequency of thrombosis, but the relationship of both thrombosis and JAK2 V617F allele burden with platelet turnover, acquired activated protein C resistance (aAPCR), and levels of coagulation factors and soluble markers of platelet, and …Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited. Busulfan is effective as first-line therapy, but there is scarce information on this drug as second-line treatment. The efficacy of busulfan in patients … NGS might be a useful diagnostic tool in NC-SVT. Lay summary: Next-generation sequencing (NGS) performs massive sequencing of DNA allowing the simultaneous evaluation of multiple genes even at very low mutational levels. Application of this technique in a cohort of patients with non-cirrhotic non-tumoral portal vein thrombosis (NC-SVT) and a ... Sep 17, 2019 · Larran's Key Buffs: Bolts/ Arrows- I'm completely fine with this +1; Cerberus Boots- Maybe just dragon boots (or) or something not Cerberus boots -1; Dominion Tower gloves- Again this isn't necessary -1; Remove Godswords- I kind of like the variety and ease of getting the lesser used Godswords and each of them have a place in terms of ... Contact Us. In order for our team to best serve you,please complete: Contact Us Form ; Help Line 1-866-452-7726Manuel Larrán-Jorge [email protected] Español. Doctor en Ciencias Económicas y Empresariales por la Universidad de Cádiz, España. Catedrático universitario, Departamento de Economía Financiera y Contabilidad. Decano de la Facultad de Ciencias Económicas y Empresariales de la Universidad de Cádiz. Tiziano Barbui 1 , Alessandro Maria Vannucchi 2 , Alberto Alvarez-Larran 3 , Alessandra Iurlo 4 , Arianna Masciulli 5 , Alessandra Carobbio 5 , Arianna Ghirardi 5 , Alberto Ferrari 5 , Giuseppe Rossi 6 , Elena Elli 7 , Marcio Miguel Andrade-Campos 8 , Mercedes Gasior Kabat 9 , Jean-Jaques Kiladjian 10 , Francesca Palandri 11 , Giulia Benevolo ...Sorry for the print in video, I received uncut rubys, worth about 54k.Unlock, Check. Examine. A secure chest. Map. Advanced data. Object ID. 34829. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player. Mar 5, 2021 · GoFundMe. Three men who spent the past 24 years behind bars for the double slaying of an off-duty NYPD cop and Queens businessman were ordered freed from prison Friday — after a judge ruled they ... The present study assessed the criteria for initiating cytoreduction and response to conventional therapies in 1446 patients with essential thrombocythemia (ET), 267 (17%) of which were CALR-mutated. In low risk patients, time from diagnosis to cytoreduction was shorter in CALR-positive than in the … Larran, Inc in Fenton, MO received a Paycheck Protection Loan of $137,615 through Midwest BankCentre, which was approved in April, 2020. This loan's status is reported by the SBA as "Paid in Full", which includes both loans repaid and those fully forgiven from repayment under PPP guidelines. The loan's status was last updated by the SBA in ...Wildy Slayer/ Larran's Keys : r/2007scape. I feel like I am one of the few people left in this game who still enjoys this very dead part of the game. I saw exactly 5 pkers during my time collecting these keys. Please buff this dead content, at least give us the emblems back : (. Also feel free to message me here or in game if your looking to ... Mar 30, 2021 · Abstract. Treatment modalities for polycythemia vera (PV) have evolved over time. Phlebotomy and low-dose aspirin suffice in low-risk patients, but cytoreductive therapies are indicated in all high-risk patients (age ≥ 65 years or those with a history of PV-related thrombotic event) and may be considered for low-risk patients with ... Abstract. Ursolic acid (UA) is a pentacyclic triterpenoid widely found in herbs, leaves, flowers and fruits; update information on the major natural sources or agro-industrial wastes is presented. Traditional (maceration, Soxhlet and heat reflux) and modern (microwave-, ultrasound-, accelerated solvent- and supercritical fluid) extraction and ... The expert panel agreed on 33 statements, reflecting a consensus, which will guide clinical decision making for patients with hematological neoplasms during the COVID-19 pandemic.Pablo Larraín’s Maria Callas biopic starring Angelina Jolie, a mystery thriller created by Jim Keeble and Dudi Appleton are the first projects to be backed by Fremantle and IBI Investment House ...The Home Depot Pro Specialty Trades, formerly Leran Gas Products, is becoming HD Supply. That means one-stop convenience and access to the essential supplies, resources, and tools that your business demands. We are here to help make your job easier, and are still your single-source supplier for everything from gas products and electrical ...Buying larrans keys! : r/2007scape. 13 comments. Best. Add a Comment. RS_Complain • 1 yr. ago. FYI keys are currently selling for 450K per key in the collection log discord. whypvmersmadge • 1 yr. ago. You're ruining the mans merching attempt. Lazy_Inferno. Current Guide Price 134.3k. Today's Change - 2,154 - 1%. 1 Month Change - 34.4k - 20%. 3 Month Change 48.8k + 57%.Current Guide Price 134.3k. Today's Change - 2,154 - 1%. 1 Month Change - 34.4k - 20%. 3 Month Change 48.8k + 57%. Current Guide Price 134.3k. Today's Change - 2,154 - 1%. 1 Month Change - 34.4k - 20%. 3 Month Change 48.8k + 57%.NGS might be a useful diagnostic tool in NC-SVT. Lay summary: Next-generation sequencing (NGS) performs massive sequencing of DNA allowing the simultaneous evaluation of multiple genes even at very low mutational levels. Application of this technique in a cohort of patients with non-cirrhotic non-tumoral portal vein thrombosis (NC-SVT) and a ... Currently working as a postdoc researcher at the Center for Research in Agricultural Genomics (CRAG) in Spain. My research line is focused on the mechanisms controlling epigenetic silencing in plants.8699. Larran is a non-player character found north-east of the Chaos Temple by his small chest . If players speak to him while wearing a ghostspeak amulet, they will learn that he was once a wealthy merchant who stored his possessions in a small and big chest in the Wilderness, where he believed few would attempt to open them. A secure chest. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player. Though sharing the same loot compared to Larran's small chest, the quantities obtained from the big chest are much ... Need A New Computer/Laptop? Use Code "nosleep5" for 5% off ALL IronSide products! Benefits me a ton.https://ironsidecomputers.com/mintmadcow channel - https:...• social responsibility • ethics Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by clonal expansion of an abnormal hematopoietic stem/progenitor cell that leads to an increased red blood cell mass as the main clinical feature; elevated white blood cell and platelet counts are also common. 1 PV is almost always genetically characterized by the presence of an activating JAK2 mutation, primarily ...OSRS Larran’s key is a new Wilderness key obtained from killing runescape gold monsters while on a slayer assignment. Similar to the Brimstone key, you can use the Larran’s Key to open OSRS Larran’s chest for some rewards. According to the latest official news post, there is now a chance of dropping Larran’s Key OSRS from Slayer tasks ...www.thelancet.com/haematology Vol 9 April 2022 e301 Review Lancet Haematol 2022; . 9: e301–11 Hematology and Transplant . Unit, Azienda Ospedaliera SS Antonio e ...Current Guide Price 134.3k. Today's Change - 2,154 - 1%. 1 Month Change - 34.4k - 20%. 3 Month Change 48.8k + 57%. The Home Depot Pro Specialty Trades, formerly Leran Gas Products, is becoming HD Supply. That means one-stop convenience and access to the essential supplies, resources, and tools that your business demands. We are here to help make your job easier, and are still your single-source supplier for everything from gas products and electrical ... • social responsibility • ethics17/1. 78/20. Source: CricketArchive, 24 December 2022. Lauren Winfield-Hill ( née Winfield; born 16 August 1990) is an English cricketer who currently plays for Yorkshire, Northern Diamonds, Oval Invincibles, Melbourne Stars and England. She plays as a right-handed batter and occasional wicket-keeper. Nov 18, 2019 · OSRS Larran’s key is a new Wilderness key obtained from killing runescape gold monsters while on a slayer assignment. Similar to the Brimstone key, you can use the Larran’s Key to open OSRS Larran’s chest for some rewards. According to the latest official news post, there is now a chance of dropping Larran’s Key OSRS from Slayer tasks ... Clinical characteristics, prognosis and treatment of myelofibrosis patients with severe thrombocytopenia A secure chest. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player. Though sharing the same loot compared to Larran's small chest, the quantities obtained from the big chest are much ...Larran's key is a key obtained from killing monsters while on a Slayer task given by Krystilia. It is used to open Larran's small and big chests. The exact odds of receiving a key scales with the monster's Combat level. For levels 1-80, the probability follows a curve between 1/1972 at level 1 to 1/100 at level 80.Pablo Larraín’s Maria Callas biopic starring Angelina Jolie, a mystery thriller created by Jim Keeble and Dudi Appleton are the first projects to be backed by Fremantle and IBI Investment House ...The “Goodfellas” star recently joined her costars Michael Imperioli and Steve Schirripa on their podcast “Talking Sopranos” and reflected on her annoyance with her character’s exit. “I ...Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited. Busulfan is effective as first-line therapy, but there is scarce information on this drug as second-line treatment. The efficacy of busulfan in patients … 17/1. 78/20. Source: CricketArchive, 24 December 2022. Lauren Winfield-Hill ( née Winfield; born 16 August 1990) is an English cricketer who currently plays for Yorkshire, Northern Diamonds, Oval Invincibles, Melbourne Stars and England. She plays as a right-handed batter and occasional wicket-keeper.Hematocrit control below 45% is associated with a lower rate of thrombosis in polycythemia vera. In patients receiving hydroxyurea, this target can be achieved with hydroxyurea alone or with the combination of hydroxyurea plus phlebotomies. However, the clinical implications of phlebotomy requiremen …- Because Larran's Keys are always lost on death, suiciding to have time in the Wilderness without risking everything would have meant losing the keys. In order to circumvent this, you'd have to travel to Larran's big chest and cash in any keys you have (probably 1 or 2 most of the time) before suiciding again. The exp is far faster, many of the tasks are fully afk-able, the loot is fantastic,and I'm drowning in slayer points. It's so afk even when 3 iteming that I can afk most tasks in my phone and simply check the loot every couple minutes. If I get a larran's key I teleport out and come back.An icon used to represent a menu that can be toggled by interacting with this icon.

Haemolysis of serum samples is the leading cause of preanalytical errors in clinical laboratories. Little is known about the potential alterations in the concentrations of mineral elements in haemolyzed serum and the phenomenon has not been specifically studied in bovine serum samples. We investigat …. Comings and goings on yandr

Abstract. Treatment modalities for polycythemia vera (PV) have evolved over time. Phlebotomy and low-dose aspirin suffice in low-risk patients, but cytoreductive therapies are indicated in all high-risk patients (age ≥ 65 years or those with a history of PV-related thrombotic event) and may be considered for low-risk patients with ...Criteria of response and definition of resistance and intolerance to hydroxyurea (HU) in polycythemia vera (PV) were proposed by the European LeukemiaNet (ELN). Such criteria were evaluated in 261 PV patients (median follow-up, 7.2 years) treated with HU for a median of 4.4 years. Complete response, …Myelofibrosis (MF) is a clonal myeloproliferative neoplasm, typically associated with disease-related symptoms, splenomegaly, cytopenias and bone marrow fibrosis. Patients experience a significant symptom burden and a reduced life expectancy. Patients with MF receive ruxolitinib as the current stand …Angelina Jolie will star in Oscar-nominated director Pablo Larraín’s next movie, a biopic about famous opera singer Maria Callas. Titled “Maria,” the film “tells the tumultuous, beautiful ...Silvina Larran Passion fruit (Passiflora edulis Sims.) is a subtropical fruit recently cultivated in Misiones Province, Argentina. In spring 1997, a severe epidemic of anthracnose was observed.Larran, Inc in Fenton, MO received a Paycheck Protection Loan of $137,615 through Midwest BankCentre, which was approved in April, 2020. This loan's status is reported by the SBA as "Paid in Full", which includes both loans repaid and those fully forgiven from repayment under PPP guidelines. The loan's status was last updated by the SBA in ...Unlock, Check. Examine. A secure chest. Map. Advanced data. Object ID. 34829. Larran's big chest can be found on the ship west of Pirates' Hideout. The chest is locked and can only be opened by using Larran's key, which is obtained from killing monsters that Krystilia assigns the player. The present study assessed the criteria for initiating cytoreduction and response to conventional therapies in 1446 patients with essential thrombocythemia (ET), 267 (17%) of which were CALR-mutated. In low risk patients, time from diagnosis to cytoreduction was shorter in CALR-positive than in the …Sorry for the print in video, I received uncut rubys, worth about 54k.NGS might be a useful diagnostic tool in NC-SVT. Lay summary: Next-generation sequencing (NGS) performs massive sequencing of DNA allowing the simultaneous evaluation of multiple genes even at very low mutational levels. Application of this technique in a cohort of patients with non-cirrhotic non-tumoral portal vein thrombosis (NC-SVT) and a ... Clinical characteristics, prognosis and treatment of myelofibrosis patients with severe thrombocytopenia Buying larrans keys! : r/2007scape. 13 comments. Best. Add a Comment. RS_Complain • 1 yr. ago. FYI keys are currently selling for 450K per key in the collection log discord. whypvmersmadge • 1 yr. ago. You're ruining the mans merching attempt. Lazy_Inferno.We assessed the benefit/risk of low-dose aspirin in 433 patients with low-risk essential thrombocythemia (271 with a CALR mutation, 162 with a JAK2 (V617F) mutation) who were on antiplatelet therapy or observation only. After a follow up of 2215 person-years free from cytoreduction, 25 thrombotic and 17 bleeding episodes were recorded..

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